Repeatedly asked questions / Frequently asked questions on coagulants and anticoagulants

Repeatedly asked questions / Frequently asked questions on coagulants and anticoagulants

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Definition: An agent that produces coagulation (Coagulation is a complex process by which blood forms clots).
Definition: An anticoagulant is a substance that prevents coagulation; that is, it stops blood from clotting

What are coagulant drugs?
Coagulation modifiers are drugs that act on the blood coagulation pathway in different places to prevent or promote blood clot formation. Anticoagulants and antiplatelet drugs are used to prevent blood clot formation.

What are examples of anticoagulants?
Anticoagulants include:
apixaban (Eliquis)
dabigatran (Pradaxa)
edoxaban (Lixiana)
rivaroxaban (Xarelto)
warfarin (Coumadin)

What is the difference between clotting and coagulation?
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. ... Coagulation is highly conserved throughout biology. In all mammals, coagulation involves both a cellular (platelet) and a protein (coagulation factor) component.

What are anticoagulants used for?
Anticoagulants are medicines that help prevent blood clots. They're given to people at a high risk of getting clots, to reduce their chances of developing serious conditions such as strokes and heart attacks.

Who should not take anticoagulants?
Things that can raise your risk include:
Age. Being older than 65 raises your risk.
Gender. Being a woman raises your risk.
Heart failure.
High blood pressure.
A previous stroke or transient ischemic attack (TIA).
Heart attack, peripheral arterial disease, or other blood vessel disease.
Diabetes.

What is the best anticoagulant drug?
In the last few years, FDA has approved three new oral anticoagulant drugs – Pradaxa (dabigatran), Xarelto (rivaroxaban), and Eliquis (apixaban). Like warfarin, all three are 'blood thinners' that reduce the overall risk of stroke related to atrial fibrillation but they also cause bleeding

What are natural anticoagulants?
The most important natural anticoagulants are protein C, protein S, and antithrombin (which used to be called antithrombin III until its name was changed to antithrombin). Figure. The normal balance between clotting and bleeding is disrupted when there is a deficiency of one of the natural anticoagulants



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